Psoriasis is a widespread disease that affects 2-3% of the world population. Although it has been known for 2000 years, its pathogenetic mechanisms have not been clarified yet. Certainly, the pathogenesis is complex and multifactorial. First of all, genetic factors come into play: the incidence of the disease has increased in HLACW6 and / or HLA-DR7 positive individuals, even if the penetration of the genes appears to be quite low and their expression irregular….

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